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杨坦,博士,AG真人国际药理学系副教授,研究生导师,“博新人才”
研究方向:药物递送系统,模式动物,药代动力学。
电 话:13377890467
邮 箱:yangtan0120@hust.edu.cn
地 址:武汉市航空路13号AG真人国际1号楼609室
教育与工作经历
2020.10—至今 AG真人国际同济医学院AG真人国际 副教授
2018.07—2020.10 AG真人国际同济医学院AG真人国际 讲师
2016.07—2018.07 AG真人国际 免疫学 博士后
2011.09—2016.06 AG真人国际 药物化学 博士
2006.09—2011.06 安徽医科大学 临床药理学 学士
主持或参与科研项目(课题)及人才计划项目情况
国家自然科学基金青年项目,编号81703446,2018/01-2020/01,20万元,主持。
博士后创新人才支持计划,编号BX201600057,2016/8.19-2018/8.19,20万,主持。
博士后面上基金,编号2017M612474,5万元,主持。
AG真人国际人才引进基金,2019.03–2022.03, 20万,主持。
国家自然科学基金面上项目,81673368,2017/01-2020/12,70万元,参加。
国家自然科学基金青年项目,81603046,2017/01-2019/12,17.5万元,参加。
国家自然科学基金面上项目,81572723,2016/01-2019/12,66万元,参加。
国家自然科学基金面上项目,81370058,2014/01-2017/12,70万元,参加。
国家自然科学基金青年项目,81201553,2013/01-2015/12,23万元,参加。
主要学术论文
(1)Xiaojuan Zhang, Chuanchuan He, Yan Chen, Chen Chen , Ruicong Yan , Ting Fan, Yongkang Gai,Tan Yang*, Yao Lu*, Guangya Xiang*,Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy,BIOMATERIALS,2021,275:120987 (IF=12.4)
(2) Yan Chen , Chen Chen , Xiaojuan Zhang, Chuanchuan He, Pengxuan Zhao, Minsi Li, Ting Fan, Ruicong Yan, Yao Lu, Robert J. Lee, Muhammad Waseem Khan, Muhammad Sarfraz, Xiang Ma*,Tan Yang*, Guangya Xiang*, Platinum complexes of curcumin delivered by dual-responsive polymeric nanoparticles improve chemotherapeutic efficacy based on the enhanced anti-metastasis activity and reduce side effects,Acta Pharmaceutica Sinica B,2020,10(6):1106-1121(IF=11.4)
(3) Weijie Li, Ruicong Yan, Yong Liu, Chuanchuan He, Xiaojuan Zhang, Yao Lu, Muhammad Waseem Khan, Chuanrui Xu,Tan Yang*and Guangya Xiang*,Co-delivery of Bmi1 small interfering RNA with ursolic acid by folate receptor-targeted cationic liposomes enhances anti-tumor activity of ursolic acid in vitro and in vivo,DRUG DELIVERY,2019:26 , 794–802(IF=6.4)
(4) Chuanchuan He#, Xiaojuan Zhang#, Ruicong Yan, Pengxuan Zhao, Yan Chen, Minsi Li, Chen Chen, Ting Fan, Yao Lu, Chen Wang, Fan Wu, Robert J. Lee,Tan Yang*and Guangya Xiang*,Enhancement of cisplatin efficacy by lipid–CaO2 nanocarrier-mediated comprehensive modulation of the tumor microenvironment,Biomaterials Science,2019, 7(10):4260-4272(IF=6.8)
(5)Tan Yang, Yuyuan Chen, Pengxuan Zhao, Huiying Xue, Jia You, Bin Li, Yong Liu, Chuanchuan He, Xiaojuan Zhang, Lingling Fan, Robert J. Lee, Lei Li, Xiang Ma, Chuanrui Xu*, Guangya Xiang*,Enhancing the Therapeutic Effect via Elimination of Hepatocellular Carcinoma Stem Cells using Bmi1 siRNA Delivered by Cationic Cisplatin Nanocapsules,Nanomedicine: Nanotechnology, Biology, and Medicine,2018:14 2009–2021(IF=6.4)
(6) Yang Tan#,Xu Ling#,Li Bin,Li Weijie,Ma Xiang,Fan Lingling,Robert J Lee,Xu Chuanrui*,Xiang Guangya*,antitumor activity of a folate receptor-targeted immunoglobulin g-doxorubicin conjugate,International Journal of Nanomedicine,2017:12 2505~2515 (IF=4.3)
(7) Yang Tan,Zhao Pengxuan,Rong Zhao,Li Bin,Xue Huiying,You Jia,He Chuanchuan,Li Weijie,He Xinxin,Robert J Lee,Ma Xiang*,Xiang Guangya*,Anti-tumor Efficiency of Lipid-coated Cisplatin Nanoparticles Co-loaded with MicroRNA-375,Theranostics,2016, 6(1): 142~154 (IF=11.5)
(8) Huang Yifei#,Yang Tan#,Zhang Wendian,Lu Yao,Ye Peng,Yang Guang,Li Bin,Qi Shibo,Liu Yong,He Xingxing,Robert J Lee,Xu Chuanrui*,Xiang Guangya*,a novel hydrolysis-resistant lipophilic folate derivative enables stable delivery of targeted liposomes in vivo,International Journal of Nanomedicine,2014,9:4581~4595 (IF=4.3)
(9) Yang Tan,Li Bin,Qi Shibo,Liu Yong,Gai Yongkang,Ye Peng,Yang Guang,Zhang Wendian,Zhang Peng,He Xingxing,Li Weijie,Zhang Zhiping,Xiang Guangya*,Xu Chuanrui*,Co-delivery of Doxorubicin and Bmi1 siRNA by Folate Receptor Targeted Liposomes Exhibits Enhanced Anti-Tumor Effects in vitro and in vivo,Theranostics,2014,4(11):1096~1111 (IF=11.5)